What is peocedure of equipment cleaning and how nay type and how to calculate MACO?

Question

Accepted Answer

Equipment cleaning procedure involves thorough cleaning and sanitization to prevent contamination. MACO is calculated based on the maximum allowable carryover of a product.

Equipment cleaning should follow a detailed procedure outlined in the standard operating procedures (SOPs)
Different types of cleaning agents may be used based on the equipment and the substances it comes in contact with
MACO calculation involves determining the maximum allowable carryover of a product on the equipment surface
MACO can be calculated using the formula: MACO = (A/B) x C, where A is the acceptable daily intake of the product, B is the batch size, and C is the equipment surface area

Asked in Ipca Laboratories

What is peocedure of equipment cleaning and how nay type and how to calculate MACO?

Interview Questions Asked to Senior Executive QA at Other Companies