Senior Scientist - ADC Medicinal Chemistry

Preferred candidate profile:

PhD (Organic chemistry / Medicinal chemistry) with 5 -6 years of experience in antibody drug conjugates (ADC) development

Roles & Responsibilities:

• Must have hands on experience in linker- payload synthesis and overall understanding of ADC.
• Should be able to design and execute synthesis of complex drug linkers and ADC payloads.
• Should have proficiency in characterization and analysis of synthesized molecules using analytical techniques such as HPLC, LC-MS and NMR.
• Thorough understanding of linker chemistry and latest development in the space.
• Efficient employment of structure-based drug design principles and integrate with other experimental data collected in the design of new linkers.
• Mentor and manage team members for high performance and scientific growth.
• Collaborate with project team members and communicate progress against goals in a multidisciplinary setting: chemistry, antibody engineering, biology, pharmacology, DMPK, and external collaborators.
• Accurate documentation of experiment and maintaining a well-organized laboratory notebook (LNB).
• Understanding of systems and process related to safety, health, and environment (SHE).