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HPLC testing includes various techniques for separating and analyzing compounds in complex mixtures.
Reversed-Phase HPLC: Commonly used for pharmaceuticals, separating non-polar compounds.
Normal-Phase HPLC: Utilizes polar stationary phases, suitable for polar compounds.
Ion-Exchange HPLC: Ideal for separating charged molecules, often used in protein analysis.
Size-Exclusion HPLC: Separates molecules based on size, us...
Chirality refers to the property of a molecule having non-superimposable mirror images, crucial in pharmaceuticals and biochemistry.
Chiral molecules exist in two forms: enantiomers, which are mirror images of each other.
Example: Lactic acid has two enantiomers, L-lactic acid and D-lactic acid, with different biological activities.
Chirality is important in drug development as different enantiomers can have differen...
Chiral testing identifies enantiomers, while RS testing assigns configuration to chiral centers in compounds.
Chiral testing focuses on the optical activity of molecules, determining if they are enantiomers.
RS testing assigns R (rectus) or S (sinister) configuration based on the Cahn-Ingold-Prelog priority rules.
Example of chiral testing: Identifying D- and L-amino acids in a sample.
Example of RS testing: Determini...
Tablets can be categorized into different types based on their formulation and release mechanisms.
Immediate release tablets
Extended release tablets
Chewable tablets
Effervescent tablets
Enteric-coated tablets
Excipients are inactive ingredients used in tablet formulation to help with the manufacturing process, stability, and appearance of the tablet.
Excipients can include fillers, binders, disintegrants, lubricants, and coloring agents.
Examples of excipients are microcrystalline cellulose (filler), magnesium stearate (lubricant), and croscarmellose sodium (disintegrant).
HPLC stands for High Performance Liquid Chromatography, a technique used to separate, identify, and quantify components in a mixture.
HPLC involves a mobile phase (liquid solvent) and a stationary phase (solid support).
The sample mixture is injected into the HPLC system and carried by the mobile phase through the stationary phase.
Different components in the mixture interact differently with the stationary phase, le...
I appeared for an interview in Oct 2024, where I was asked the following questions.
Detail-oriented Quality Control Officer with a passion for ensuring product excellence and compliance with industry standards.
Over 5 years of experience in quality control in manufacturing environments.
Skilled in conducting inspections and audits to ensure compliance with ISO standards.
Implemented a new quality management system that reduced defects by 20%.
Strong analytical skills, able to identify trends and areas for...
As a Quality Control Officer, I ensure product quality through inspections, testing, and compliance with industry standards.
Conduct regular inspections of products to identify defects and ensure compliance with quality standards.
Develop and implement quality control procedures, such as sampling plans and testing protocols.
Analyze data from quality tests to identify trends and areas for improvement.
Collaborate with prod...
Chiral testing identifies enantiomers, while RS testing assigns configuration to chiral centers in compounds.
Chiral testing focuses on the optical activity of molecules, determining if they are enantiomers.
RS testing assigns R (rectus) or S (sinister) configuration based on the Cahn-Ingold-Prelog priority rules.
Example of chiral testing: Identifying D- and L-amino acids in a sample.
Example of RS testing: Determining th...
I applied via Campus Placement and was interviewed before Oct 2022. There were 2 interview rounds.
HPLC stands for High Performance Liquid Chromatography, a technique used to separate, identify, and quantify components in a mixture.
HPLC involves a mobile phase (liquid solvent) and a stationary phase (solid support).
The sample mixture is injected into the HPLC system and carried by the mobile phase through the stationary phase.
Different components in the mixture interact differently with the stationary phase, leading...
Tablets can be categorized into different types based on their formulation and release mechanisms.
Immediate release tablets
Extended release tablets
Chewable tablets
Effervescent tablets
Enteric-coated tablets
Excipients are inactive ingredients used in tablet formulation to help with the manufacturing process, stability, and appearance of the tablet.
Excipients can include fillers, binders, disintegrants, lubricants, and coloring agents.
Examples of excipients are microcrystalline cellulose (filler), magnesium stearate (lubricant), and croscarmellose sodium (disintegrant).
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posted on 15 Apr 2018
I applied via Naukri.com and was interviewed in Jul 2017. There were 6 interview rounds.
posted on 10 Jul 2017
I appeared for an interview before Jul 2016.
I applied via Campus Placement and was interviewed before May 2020. There were 3 interview rounds.
I applied via Referral and was interviewed in Mar 2020. There was 1 interview round.
Data integrity is crucial for accurate decision-making and maintaining trust in the organization.
Data integrity ensures that data is accurate, complete, and consistent.
It is important to have proper data management policies and procedures in place.
Regular data audits and checks should be conducted to ensure data integrity.
Examples of data integrity violations include data entry errors, system glitches, and unauthorized...
posted on 26 Oct 2020
I applied via Naukri.com and was interviewed in May 2020. There were 5 interview rounds.
I applied via Company Website and was interviewed in Nov 2019. There were 3 interview rounds.
I was a Senior Sales Associate responsible for managing a team of sales representatives and achieving sales targets.
Managed a team of sales representatives
Set and achieved sales targets
Provided training and guidance to new team members
Analyzed sales data and implemented strategies to improve performance
A PID temperature indicator controls temperature by adjusting heating/cooling based on feedback from sensors.
PID stands for Proportional-Integral-Derivative, which are the three control modes used to adjust temperature.
The indicator receives input from temperature sensors and compares it to the desired temperature setpoint.
Based on the difference between the two, the PID controller adjusts the heating/cooling output to...
Utility distribution systems ensure efficient delivery of essential services like water, electricity, and gas to designated areas.
Design involves assessing the demand for utilities in the block based on population and usage patterns.
Incorporate sustainable practices, such as using renewable energy sources for electricity distribution.
Example: For a residential block, design a grid layout for electricity that minimizes ...
MTSR, DSC, and TSC are metrics used in call centers to measure performance and efficiency.
MTSR stands for Mean Time to Service Request and measures the average time it takes for a customer's service request to be resolved.
DSC stands for Delayed Service Calls and measures the number of service calls that were not resolved within a certain timeframe.
TSC stands for Total Service Calls and measures the total number of serv...
XRD is a technique used to determine the crystal structure of a material. Crystalline and amorphous materials show different patterns.
XRD stands for X-ray diffraction
Crystalline materials have a regular, repeating pattern of atoms while amorphous materials lack this pattern
XRD patterns of crystalline materials show sharp peaks while amorphous materials show broad peaks
XRD can be used to identify unknown crystalline mat...
The degree of freedom of water at triple point is 0.
Triple point is the temperature and pressure at which solid, liquid, and gas phases of a substance coexist in thermodynamic equilibrium.
At triple point, the degree of freedom of a substance is zero because all three phases coexist in equilibrium.
Water has a triple point at 273.16 K (0.01 °C) and a pressure of 611.73 Pa.
At triple point, water can exist as ice, liquid w...
Risk is the possibility of loss or harm occurring due to uncertain events or circumstances.
Risk involves uncertainty and the potential for negative consequences.
It can be managed through risk assessment, mitigation, and transfer.
Examples of risks include financial risks, health risks, and environmental risks.
Risk can also present opportunities for growth and innovation.
The power required for a pump can be calculated using the formula: Power = (Flow rate x Head) / Efficiency
Calculate the flow rate of the pump
Determine the head or pressure required
Consider the efficiency of the pump
Use the formula: Power = (Flow rate x Head) / Efficiency
Example: If the flow rate is 1000 liters per minute, the head is 50 meters, and the efficiency is 80%, the power required would be (1000 x 50) / 0.8 = ...
I applied via Recruitment Consultant and was interviewed in Nov 2020. There were 4 interview rounds.
HPLC troubleshooting involves identifying and resolving issues with the equipment or method.
Check for air bubbles in the system
Verify column temperature and mobile phase composition
Inspect the detector and ensure proper calibration
Review sample preparation and injection volume
Consult instrument manual or technical support for further assistance
AV value in CU test is calculated by dividing the average of the duplicate readings by the standard solution value.
AV value stands for Average Value.
CU test is a test used to determine the copper content in a sample.
Duplicate readings are taken to ensure accuracy.
The standard solution value is a known concentration of copper used as a reference.
AV value = (Average of duplicate readings) / (Standard solution value)
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