Rubicon Research Interview Questions and Answers

Guidelines for RS tests focus on accuracy, method validation, and impurity assessment in samples.

• Ensure proper calibration of instruments before conducting RS tests.

• Use validated methods for sample preparation to minimize contamination.

• Assess impurities by comparing sample spectra with reference standards.

• Document all findings and deviations during the testing process.

• Implement quality control measures, such as ru...read more

The method development process involves designing, optimizing, and validating analytical methods for specific applications.

• Define the objective: Determine the purpose of the method, such as quantifying a specific compound.

• Select the appropriate technique: Choose between methods like HPLC, GC, or spectrophotometry based on the analyte.

• Optimize conditions: Adjust parameters like temperature, pH, and flow rate to imp...read more

GTIN stands for Global Trade Item Number, a unique identifier for products used in global commerce.

• GTIN is used to uniquely identify products in the supply chain.

• It can be represented in various formats, including GTIN-8, GTIN-12, GTIN-13, and GTIN-14.

• GTIN-13 is commonly used as the barcode on retail products.

• Example: A GTIN-13 for a specific product might look like 0123456789012.

CQA stands for Critical Quality Attributes and CPP stands for Critical Process Parameters for tablets and capsules.

• CQA are the key physical, chemical, biological, or microbiological characteristics that must be within an appropriate limit, range, or distribution to ensure the desired product quality.

• CPP are the key process parameters that should be controlled within a narrow range or set points to ensure the produ...read more

Process validation types include prospective, retrospective, and concurrent validation.

• Prospective validation involves establishing specifications and procedures before production.

• Retrospective validation involves reviewing historical data to verify processes were consistently in control.

• Concurrent validation involves monitoring and evaluating processes during production.

• Examples: Prospective validation - setting ...read more

The number of samples analyzed per day varies depending on the workload and complexity of the samples.

• The number of samples analyzed per day can range from 50 to 200, depending on the size of the laboratory and the efficiency of the processes.

• Factors such as the type of analysis required, equipment availability, and staff expertise can also impact the number of samples analyzed per day.

• For example, in a high-throu...read more

Quality assurance is the process of ensuring that products or services meet the desired level of quality.

• It involves creating and implementing quality control procedures

• It ensures that products or services meet customer expectations

• It involves continuous monitoring and improvement of processes

• Examples include conducting inspections, testing products, and analyzing data

• It is important for maintaining customer satis...read more

Stratified sampling is a method of sampling that involves dividing a population into subgroups and sampling from each subgroup.

• It ensures representation from all subgroups, enhancing the accuracy of results.

• For example, in a study on student performance, you might stratify by grade level.

• Another example is in market research, where you might stratify by age or income level.

• Stratified sampling can reduce sampling e...read more